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Table 3 Sensitivity (per-patient) and specificity using BI-RADS score of at least 4 to define a positive test

From: Dual-energy contrast-enhanced digital mammography: initial clinical results of a multireader, multicase study

Reader MX ± US MX ± US ± CEDM Difference Pvalue
Sensitivity
1 0.875 ± 0.042 0.922 ± 0.034 0.047 0.25
2 0.953 ± 0.027 0.938 ± 0.030 -0.016 1.00
3 0.922 ± 0.034 0.938 ± 0.030 0.016 1.00
4 0.969 ± 0.022 0.953 ± 0.027 -0.016 1.00
5 0.938 ± 0.030 0.859 ± 0.044 -0.078 0.07
6 0.875 ± 0.042 0.906 ± 0.037 0.031 0.68
Overall 0.922 ± 0.028 0.919 ± 0.031 -0.003 ± 0.022 0.91
95% CI 0.866 to 0.977 0.858 to 0.981 -0.052 to 0.047
Specificity
1 0.565 ± 0.074 0.457 ± 0.074 -0.109 0.18
2 0.478 ± 0.074 0.587 ± 0.073 0.109 0.23
3 0.413 ± 0.073 0.457 ± 0.074 0.043 0.68
4 0.174 ± 0.057 0.239 ± 0.064 0.065 0.37
5 0.326 ± 0.07 0.413 ± 0.073 0.087 0.34
6 0.565 ± 0.074 0.609 ± 0.073 0.043 0.77
Overall 0.42 ± 0.073 0.46 ± 0.071 0.040 0.336
95% CI 0.262 to 0.578 0.308 to 0.613 -0.046 to 0.126
  1. Values are presented as estimate ± standard error unless otherwise indicated. BI-RADS, Breast Imaging, Reporting and Data System; CEDM, contrast-enhanced digital mammography; CI, confidence interval; MX, mammography; US, ultrasonography.
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