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Table 1 Characteristics of patients with endometrial cancer after breast cancer, by study

From: Endometrial cancer survival after breast cancer in relation to tamoxifen treatment: Pooled results from three countries

  Study Total
  NL UK US   
  N % N % n % N %
Age at diagnosis of breast cancer (years)
   < 45 40 5.2 36 4.6 6 1.9 82 4.4
   45 to 54 147 19.2 170 21.6 35 10.8 352 18.8
   55 to 64 231 30.2 256 32.6 108 33.3 595 31.7
   65 to 74 246 32.2 224 28.5 119 36.7 589 31.4
   75 to 84 91 11.9 92 11.7 47 14.5 230 12.3
   85 and over 10 1.3 8 1.0 9 2.8 27 1.4
Age at diagnosis of endometrial cancer (years)
   < 55 72 9.4 94 12.0 24 7.4 190 10.1
   55 to 64 183 23.9 215 27.4 71 21.9 469 25.0
   65 to 74 277 36.2 238 30.3 138 42.6 653 34.8
   75 to 84 184 24.1 187 23.8 74 22.8 445 23.7
   85 and over 49 6.4 52 6.6 17 5.2 118 6.3
Year of diagnosis of breast cancer
   1972 to 1979 37 4.8 60 7.6 33 10.2 130 6.9
   1980 to 1984 98 12.8 196 24.9 122 37.7 416 22.2
   1985 to 1989 163 21.3 376 47.8 147 45.4 686 36.6
   1990 to 1995 238 31.1 150 19.1 22 6.8 410 21.9
   1995 to 1999 152 19.9 4 0.5 0 0.0 156 8.3
   2000 to 2005 77 10.1 0 0.0 0 0.0 77 4.1
Year of diagnosis of endometrial cancer
   1978 to 1984 16 2.1 0 0.0 38 11.7 54 2.9
   1985 to 1989 63 8.2 112 14.3 143 44.1 318 17.0
   1990 to 1994 141 18.4 501 63.7 143 44.1 785 41.9
   1995 to 1999 257 33.6 173 22.0 0 0.0 430 22.9
   2000 to 2006 288 37.6 0 0.0 0 0.0 288 15.4
Extent of disease (breast cancer)a
   Localized 362 47.3 317 40.3 198 61.1 877 46.8
   Regional extension 295 38.6 150 19.1 121 37.4 566 30.2
   Metastatic disease 15 2.0 4 0.5 5 1.5 24 1.3
   Unknown 93 12.2 315 40.1 0 0.0 408 21.8
Interval between breast and endometrial cancers (years)
   < 1 35 4.6 47 6.0 34 10.5 116 6.2
   1 to < 3 192 25.1 135 17.2 126 38.9 453 24.2
   3 to < 5 150 19.6 134 17.1 73 22.5 357 19.0
   5 to < 10 231 30.2 326 41.5 78 24.1 635 33.9
   10 to 29 157 20.5 144 18.3 13 4.0 314 16.8
Morphological type of endometrial cancer
   Endometrioid adenocarcinomab 636 83.1 666 84.7 278 85.8 1580 84.3
   Serous or clear cellc 64 8.4 24 3.1 20 6.2 108 5.8
   Carcinosarcomad 37 4.8 56 7.1 15 4.6 108 5.8
   Sarcomae 26 3.4 19 2.4 9 2.8 54 2.9
   Not known 2 0.3 21 2.7 2 0.6 25 1.3
All patients 765 100.0 786 100.0 324 100.0 1875 100.0
  1. aLocalized: no lymph node involvement; Regional extension: spread to lymph nodes; bEndometrial adenocarcinoma, mixed cell adenocarcinoma, papillary endometrial adenocarcinoma; cSerous adenocarcinoma, clear cell adenocarcinoma; dCarcinosarcoma, Mullerian mesodermal mixed tumors; eSarcoma, endometrial stromal adenocarcinoma, leiomyosarcoma.