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Table 1 Effect of 100 nM panobinostat on cell cycle percentage of TNBC cells.

From: Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat

  Panobinostat   G0/G1 S G2/M
MDA-MB-157 - 24 h 61.72 21.68 16.59
  + 24 h 64.3 10.83 24.87
  - 72 h 52.21 25.53 22.26
  + 72 h 54.14 9.48 36.37
MDA-MB-231 - 24 h 86.74 6.03 7.23
  + 24 h 33.04 0.5 66.46
  - 72 h 57.05 24.7 18.25
  + 72 h 37.75 2.33 59.92
MDA-MB-468 - 24 h 54.07 30.29 15.64
  + 24 h 51.55 17.01 31.44
  - 72 h 53.45 34.81 11.74
  + 72 h 52.67 16.78 30.55
BT-549 - 24 h 37.66 26.57 35.77
  + 24 h 39.76 8.61 51.63
  - 72 h 36.42 27.08 36.49
  + 72 h 42.93 3.95 53.13
  1. Data (percent gated cells) representative of two independent experiments. TNBC, triple-negative breast cancer.
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Breast Cancer Research

ISSN: 1465-542X

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