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Table 1 Effect of 100 nM panobinostat on cell cycle percentage of TNBC cells.

From: Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat

 

Panobinostat

 

G0/G1

S

G2/M

MDA-MB-157

-

24 h

61.72

21.68

16.59

 

+

24 h

64.3

10.83

24.87

 

-

72 h

52.21

25.53

22.26

 

+

72 h

54.14

9.48

36.37

MDA-MB-231

-

24 h

86.74

6.03

7.23

 

+

24 h

33.04

0.5

66.46

 

-

72 h

57.05

24.7

18.25

 

+

72 h

37.75

2.33

59.92

MDA-MB-468

-

24 h

54.07

30.29

15.64

 

+

24 h

51.55

17.01

31.44

 

-

72 h

53.45

34.81

11.74

 

+

72 h

52.67

16.78

30.55

BT-549

-

24 h

37.66

26.57

35.77

 

+

24 h

39.76

8.61

51.63

 

-

72 h

36.42

27.08

36.49

 

+

72 h

42.93

3.95

53.13

  1. Data (percent gated cells) representative of two independent experiments. TNBC, triple-negative breast cancer.
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Breast Cancer Research

ISSN: 1465-542X

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