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Figure 1 | Breast Cancer Research

Figure 1

From: In vivo breast cancer characterization imaging using two monoclonal antibodies activatably labeled with near infrared fluorophores

Figure 1

Fluorescence microscopy studies. MDA-MB-468 cells and 3T3/HER2 cells were incubated with Pan-Alexa680(ON or SQ) and Tra-ICG, respectively, for one or eight hours. The higher fluorescent signals was detected by Pan-Alexa680(SQ) especially within the tumor cells compared with Pan-Alexa680(ON) after eight hours incubation. Many bright foci could be detected by Tra-ICG at eight hours within the 3T3/HER2 cells. These signals were completely blocked by the addition of excess panitumumab or trastuzumab.

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Breast Cancer Research

ISSN: 1465-542X

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