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Table 1 List of participating studies and number of case and control subjects

From: Reproductive aging-associated common genetic variants and the risk of breast cancer

Study acronym

Study name

Study design

Case subjects

(n= 3,683)

ER+/ER- subjects

(n = 1,716/371)

Control subjects

(n = 34,174)

All subjects

(n = 37,857)

NHS-BC

Nurses' Health Study-Breast Cancer

Nested case-control

1,145 (31.1)

807/181

1,142 (3.3)

2,287 (6.0)

WGHS

Women's Genome Health Study

Prospective cohort

1,099 (29.8)

909/190

22,205 (65.0)

23,304 (61.5)

SardBC

SardiNIA Breast Cancer Study

Case-control

809 (22.0)

-

674 (2.0)

1,483 (3.9)

RSI+II

Rotterdam Study I and II

Prospective cohort

216 (5.9)

-

4,261 (12.5)

4,477 (11.8)

FHS

Framingham Heart Study

Prospective cohort

207 (5.6)

-

3,698 (10.8)

3,905 (10.3)

ARIC

Atherosclerosis Risk in Communities Study

Prospective cohort

207 (5.6)

-

2,194 (6.4)

2,401 (6.3)

  1. Data are presented as the number (percentage) of cases, controls, and all subjects. ER, estrogen receptor.