Table 3 PTEN mutations in brain metastases
From: Relevance of PTEN loss in brain metastasis formation in breast cancer patients
Sample | Mutations in gDNA | Mutations in cDNA | AI result | CGH (PTEN) | |||
|---|---|---|---|---|---|---|---|
| Â | Exon3 | Exon4 | Exon5 | Exon6 | Â | Â | result |
BrM-6 | Wt | g.del[72586_72627] | wt | nd | c.[del1241_1284] | AI | Het. loss |
BrM-7 | Wt | No product | wt | wt | Allele 1: c.[del1241_1665] Allele 2: [del1524_1665; dup1196_1240, 950_1240con1196_1523] | AI | Het. loss |
BrM-8 | wt | nd | c.389C > A | nd | nd | Normal | nd |