Skip to main content

Advertisement

Table 4 In vivo internal water reference method breast cancer literature published to date

From: In vivo proton magnetic resonance spectroscopy of breast cancer: a review of the literature

Study B0 n Method Breast cancer [Cho] range Sensitivity Specificity
Bolan et al. 2003 [32] 4 T 28 SV 0.5-8.6 mmol/kg 46% 94%
Baik et al. 2006 [55] 1.5 T 32 SV 0.76-21.20 mmol/kg NA NA
Baek et al. 2008 [56] 1.5 T 32 SV 0.32-10.47 mmol/kg NA NA
Sijens et al. 2010 [21] 1.5 T 2 MRSI 4.1 and 4.6 mmol/kg NA NA
Chen et al. 2011 [31] 1.5 T 45 SV 0.08-9.99 mmol/kg NA NA
Dorrius et al. 2011 [22] 1.5 T 24 MRSI 1.7-11.8 mmol/kg 100% 100%
Thakur et al. 2011 [57] 1.5 T 57 SV 0-47.1 mmol/kg 75-96%a 93-100%a
  1. aDepending upon choline concentration ([Cho]) cutoff value. n = number of participants with breast cancer contributing to reported [Cho] range. B0, field strength. MRSI, magnetic resonance spectroscopic imaging; NA, not applicable; SV, single-voxel; T, Tesla.