Skip to main content

Table 4 Univariate and multivariate analysis with respect to overall survival of 138 TNBC patients with surgery plus adjuvant chemotherapy or 52 TNBC patients with surgery alone

From: Advantages of adjuvant chemotherapy for patients with triple-negative breast cancer at Stage II: usefulness of prognostic markers E-cadherin and Ki67

 

Patients with chemotherapy (n= 138)

Patients without chemotherapy (n= 52)

 

Univarite analysis

Multivariate analysis

Univarite analysis

Multivariate analysis

Parameters

Odds ratio

95% CI

P-value

Odds ratio

95% CI

P- value

Odds ratio

95% CI

p value

Odds ratio

95% CI

P- value

Ki67 (+) and E-cadherin (-)

Negative vs Positive

6.69

2.41 to 18.62

<0.001

5.84

2.03 to 16.76

0.001

1.16

0.41 to 3.28

0.777

0.76

0.20 to 2.94

0.688

E-cadherin

Negative vs Positive

0.02

0.00 to 1.16

0.060

0.00

0.00 to 1.98

0.943

1.00

0.32 to 3.16

0.998

1.53

0.44 to 5.36

0.503

Ki67

Negative vs Positive

3.09

1.11 to 8.66

0.032

2.60

0.87 to 7.76

0.086

1.81

0.62 to 5.31

0.282

1.89

0.42 to 8.50

0.407

p53

Negative vs Positive

1.61

0.58 to 4.45

0.361

0.98

0.34 to 2.85

0.975

1.61

0.58 to 4.45

0.361

1.86

0.54 to 6.45

0.327

Stage

1 vs 2, 3, 4

2.56

0.73 to 8.99

0.144

0.15

0.01 to 2.45

0.185

4.22

1.17 to 15.28

0.028

1.28

0.06 to 23.36

0.872

Tumor size

≤ 2 cm vs >2 cm

2.63

0.86 to 8.01

0.089

4.23

0.54 to 33.34

0.171

23.26

1.02 to 10.38

0.046

1.65

0.16 to 16.58

0.670

Lymph node status

N0 vs N1, N2, N3

4.69

1.67 to 13.16

0.003

5.71

1.25 to 26.20

0.025

5.63

1.68 to 18.93

0.005

5.10

1.08 to 23.94

0.039

Lymphvascular invasion

Negative vs Positive

2.09

0.86 to 5.07

0.103

1.34

0.52 to 3.44

0.548

1.32

0.48 to 3.63

0.597

0.94

0.29 to 3.09

0.922

Nuclear grade

1, 2, vs 3

2.87

0.94 to 8.72

0.063

1.64

0.51 to 5.28

0.405

1.22

0.39 to 3.86

0.732

0.99

0.25 to 3.96

0.988