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Figure 2 | Breast Cancer Research

Figure 2

From: A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies

Figure 2

Composite figure showing CD8 and FoxP3 expression in lymphoid cells infiltrating representative HER2- or HER2+ breast carcinomas. (a) Few CD8+ cells are present within the tumor, and infiltrate tumor nests in a HER2- case. (b) Some FoxP3+ cells infiltrate a HER2- breast carcinoma. (c) CD8+ cells are numerous and surround tumoral cords in a HER2+ breast carcinoma. (d) Higher numbers of FoxP3+ cells infiltrate a HER2+ case. (a to d) Immunohistochemical stain; paraffin section; Hematoxylin counterstain; (a and c) 20× original magnification, (b and d) 40× magnification. HER2: human epidermal growth factor receptor-2.

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Breast Cancer Research

ISSN: 1465-542X

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