Table 2 Genotypes and allele frequencies for the ADRB2 and ADRB3 genes among all study subjects
Mean ± SD BMI (kg/m2) | |||
|---|---|---|---|
of subgrouped | |||
Genotypes and allele frequencies | Patients (n [%]) | Control individuals (n [%]) | control individuals |
Genotypes of ADRB2 | |||
Gln/Gln | 175 (87.6) | 150 (82.4) | 22.2 ± 2.9* |
Gln/Glu | 23 (11.4) | 31 (17.0) | |
Glu/Glu | 2 (1.0) | 1 (0.6) | |
Gln/Glu and Glu/Glu | 22.3 ± 3.1* | ||
Allele frequency of ADRB2 | |||
Gln | 373 (93.3) | 331 (90.9) | - |
Glu | 27 (6.7) | 33 (9.1) | - |
Genotypes of ADRB3 | |||
Trp/Trp | 140 (70.0) | 121 (66.5) | 22.3 ± 3.0† |
Trp/Arg | 56 (28.0) | 58 (31.9) | |
Arg/Arg | 4 (2.0) | 3 (1.6) | |
Trp/Arg and Arg/Arg | 22.1 ± 2.8† | ||
Allele frequency of ADRB3 | |||
Trp | 336 (84.0) | 300 (82.4) | - |
Arg | 64 (16.0) | 64 (17.6) | - |