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Table 1 Clinical data of TNBC patients from the finding-cohort-A and the validation cohorts-B and -C

From: A clinically relevant gene signature in triple negative and basal-like breast cancer

Parameter Status Finding cohort-A (n= 394) Validation cohort-B (n= 185) P-value (Chi2)
B vs A
Validation cohort-C (n= 76) P-value (Chi2)
C vs A
Lymph node status LNN 240 36   44  
  Node pos. 68 60 < 0.001 32 0.001
  n.a. 86 89   0  
Age ≤ 40 yr 63 25   10  
  41 to 50 yr 91 41   17  
  51 to 60 yr 76 39   13  
  > 60 yr 79 35 0.87 36 0.003
  n.a. 85 45   0  
Tumor size ≤ 2 cm 85 29   11  
  > 2 cm 224 122 0.068 62 0.035
  n.a. 85 34   3  
Histological grade grade 3 227 110   62  
  grade 1 and 2 82 46 0.57 14 0.18
  n.a. 85 29   0  
Biopsy method surgical 346 130   76  
  core 19 22   0  
  FNA 29 33 < 0.001 0 0.009
Five-year DFS no event 202 24   49  
  event 95 6 0.25 26 0.69
  n.a. 97 155   1