A clinically relevant gene signature in triple negative and basal-like breast cancer

Breast Cancer Research

Table 1 Clinical data of TNBC patients from the finding-cohort-A and the validation cohorts-B and -C

Parameter	Status	Finding cohort-A (n= 394)	Validation cohort-B (n= 185)	P-value (Chi²) B vs A	Validation cohort-C (n= 76)	P-value (Chi²) C vs A
Lymph node status	LNN	240	36		44
	Node pos.	68	60	< 0.001	32	0.001
	n.a.	86	89		0
Age	≤ 40 yr	63	25		10
	41 to 50 yr	91	41		17
	51 to 60 yr	76	39		13
	> 60 yr	79	35	0.87	36	0.003
	n.a.	85	45		0
Tumor size	≤ 2 cm	85	29		11
	> 2 cm	224	122	0.068	62	0.035
	n.a.	85	34		3
Histological grade	grade 3	227	110		62
	grade 1 and 2	82	46	0.57	14	0.18
	n.a.	85	29		0
Biopsy method	surgical	346	130		76
	core	19	22		0
	FNA	29	33	< 0.001	0	0.009
Five-year DFS	no event	202	24		49
	event	95	6	0.25	26	0.69
	n.a.	97	155		1

ISSN: 1465-542X