Table 1
From: Getting deep in the luminal B breast cancer subtype and its ki67 cut-off value
HER2- | ||||
|---|---|---|---|---|
Variable | HER2+ER+ | ER+PgR- | ER-PgR+ | ER+PgR+ ki67 >13 |
Cases | 189 | 126 | 10 | 385 |
Median age (P = 0.0021) | 53.49 | 60.3 | 49.7 | 57.7 |
Ductal (P = 0.002) | 173 (91.5%) | 98(77.8%) | 10 (100%) | 314 (81.5%) |
HG III (P = 0.03) | 41% | 47% | 40% | 34.1% |
Lobular | 5.3% | 17.5% | 0 | 14% |
Median ER | 85% | 83% | 0 | 90% |
Median PR | 60% | 0 | 45% | 80% |
Median ki67 | 20% | 17% | 12.5% | 20% |
Recurrences total (%) | 52 (27.5%) | 32 (25.4%) | 2 (20%) | 81 (21%) |
Locoregional | 9 (17.3%) | 3 (9.4%) | 0 | 15 (18.5%) |
Bone | 6 (11.5%) | 14 (43.8%) | 0 | 25 (30.9%) |
Visceral (P = 0.04) | 34 (65.4%) | 11 (34.4%) | 0 | 36 (44.4%) |
Median (95% CI) DFS (years) | 8.1 (6.5 to 8.7) | 6.4 (5.4 to 7.2) | 9.2 (7.6 to 11.9) | 5.6 (5.2 to 6.1) |
Median (95% CI) OS (years) | 8.7 (8.1 to 9.0) | 7.0 (5.8 to 7.9) | 10.5 (7.8 to 13.6) | 6.1 (5.6 to 6.6) |