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Figure 7 | Breast Cancer Research

Figure 7

From: erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines

Figure 7

Immunocytochemical staining. (a) Phosphorylated insulin receptor substrate 1 (IRS-1) Y612, insulin-like growth factor type I receptor (IGF-IR), Y1316, total erbB3, Akt and Ki-67 in paraffin-embedded primary clinical oestrogen-positive (ER+) breast cancer sections (original magnification, ×40). (b) Representative boxplot and scatterplot showing statistically significant correlations between immunostaining HScore values for phosphorylated membrane IRS-1 Y612 and total membrane and cytoplasmic erbB3 in the clinical ER+ breast cancer series.

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Breast Cancer Research

ISSN: 1465-542X

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