Skip to main content

Incidence and outcome of 18-fluorodeoxyglucose positron emission tomography/computed tomography-detected breast lesions

Introduction

Breast cancer accounts for around 16% of female deaths in the UK. Usual diagnosis is via the symptomatic pathway or screening. Positron emission tomography/computed tomography (PET/CT) is a modality with increasing applications in staging malignancies and investigating symptoms. It increasingly detects incidental breast lesions. The aim of this study was to evaluate the incidence and outcome of PET/CT-detected breast abnormalities.

Methods

The radiology information server (CRIS) was interrogated to produce a list of PET/CT scan results containing the word 'breast' over 4 years. Scans performed on patients with known breast malignancy were excluded. A further CRIS search was used to determine if subsequent breast imaging was performed. Pathology was obtained and hospital notes were reviewed.

Results

Thirty patients were found to have incidental breast lesions on PET/CT scanning. There were 19 masses, seven areas of focal fluorodeoxyglucose (FDG) uptake, two areas of calcification, one case of asymmetry and one area of thickening. In total, 16/30 patients underwent breast assessment (11 masses, four focal increased uptake and one bilateral calcification). Out of 11 patients with masses, six were proven to have corresponding invasive cancers and two had ductal carcinoma in situ. The remaining three were normal or had benign disease. Of the four patients with focal increased FDG uptake, one patient had invasive cancer, one had a fibroadenoma and two were normal. The bilateral calcifications corresponded to lymph nodes.

Conclusion

The incidental detection of breast malignancy by PET/CT was significant at 56%. Breast assessment should be performed in this population.

Author information

Affiliations

Authors

Corresponding author

Correspondence to LS Haine.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Cite this article

Haine, L., Rutherford, G., Ingram, C. et al. Incidence and outcome of 18-fluorodeoxyglucose positron emission tomography/computed tomography-detected breast lesions. Breast Cancer Res 13, P9 (2011). https://doi.org/10.1186/bcr2961

Download citation

Keywords

  • Breast Cancer
  • Ductal Carcinoma
  • Invasive Cancer
  • Breast Lesion
  • Breast Malignancy
\