Figure 3

IDC Associated with DCIS. a, b) Normal breast myoepithelia has is sparsely stained for AP. c) Strong enzyme activity is evident throughout the cytoplasm of the tumor cells. The AP positive granules (dark areas) are much larger than those in the control tissue (a, b). The majority of the tumor cells are AP positive, suggesting that they are undergoing cell death. d) Intense AP activity in the cords of tumor cells. Note that AP staining is absent in the stroma. X 200, a and c; X 400, b and d.