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Table 2 Correlation between MAP-tau expression and clinicopathologic variables in the Yale University cohort

From: Evaluation of prognostic and predictive value of microtubule associated protein tau in two independent cohorts

 

MAP-tau expression

 

Variable

Low (%) (AQUA score < 462)

High (%) (AQUA score > 462)

P*

Menopausal status

   

   Premenopausal

108 (22.8)

31 (6.5)

0.734

   Postmenopausal

265 (55.9)

70 (14.8)

 

Tumor size

   

   < 2 cm

128 (29.1)

31 (7.1)

0.535

   2-5 cm

155 (35.2)

50 (11.4)

 

   > 5 cm

59 (13.4)

17 (3.9)

 

Nuclear grade

   

   Small/uniform nuclei

60 (13.4)

15 (3.4)

0.225

   Intermediate nuclei

182 (40.6)

61 (13.6)

 

   Large nuclei

107 (23.9)

23 (5.1)

 

Nodal status

   

   Node positive

199 (41.8)

47 (9.9)

0.201

   Node negative

175 (36.8)

55 (11.6)

 

ER

   

   Negative

227 (48.6)

38 (8.1)

< 0.0001

   Positive

140 (29.9)

62 (13.3)

 

PR

   

   Negative

240 (52.4)

31 (6.8)

< 0.0001

   Positive

120 (26.2)

67 (14.6)

 

HER2

   

   Negative

283 (61.3)

88 (19.1)

0.010

   Positive

80 (17.3)

11 (2.4)

 
  1. *P is given for chi-square analysis. Statistically significant P values (P < 0.05) are in bold.
  2. ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor.