Figure 2

Kaplan Meier survival analysis and MAP-tau expression in Yale University cohort. (a) Ten-year survival for high MAP-tau expression versus low expression for all invasive breast carcinoma patients in the Yale University cohort (n = 651). Survival rate for patients classified as high MAP-tau expressors (n = 94) was 68.3% compared with 52.9% for low expressors (n = 339; log-rank, P = 0.006). (b) Kaplan Meier survival for MAP-tau expression stratified by eatrogen receptor (ER) status in the Yale University cohort. For ER-negative patients (inset), high MAP-tau expression (n = 35) showed improved survival compared with low (n = 209) expression. (c) Ten-year survival for MAP-tau expression stratified by human epidermal growth factor receptor (HER) 2 status in the Yale University cohort. Patients classified as high MAP-Tau expressors showed improved survival compared with low expressors, regardless of HER2 status. For ER-negative patients stratified by HER2 status (inset), ER-negative patients with high MAP-tau expression (n = 30) trended toward improved survival, regardless of HER2 status, compared with low MAP-tau expressors (n = 56) (68.4% v 45.3%; log-rank, P = 0.068).