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Figure 5 | Breast Cancer Research

Figure 5

From: NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model

Figure 5

Expression pattern in IKFM lung homogenates suggests that the majority of macrophages are M1 phenotype. RNA was isolated from whole lung samples of IKFM and control mice treated with doxycycline (dox; 2 g/L) for one week. Quantitative real-time PCR was performed for (a) CCL3, (b) mannose receptor, (c) arginase-1 and (d) TNF-alpha (P < 0.05, **P < 0.01, ***P < 0.001; n = 5 control, n = 5 IKFM).

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Breast Cancer Research

ISSN: 1465-542X

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