Table 4 Mean survival based on CTC positivity, TIMP-1 and CAIX levels

CTC negative

< 0.01¹

< 0.01¹

TIMP-1

   Non elevated

12.3(10.6-14.1)

< 0.01²

21.4 (20.3-22.6)

< 0.01

   Elevated

4.4 (2.8-6.0)

12.0 (8.2-15.7)

CTC positive

TIMP-1

   Non elevated

9.5 (7.6-11.4)

0.81

15.5 (13.3-17.7)

0.151

   Elevated

8.5 (6.2-10.8)

12.0 (9.4-14.6)

CTC negative

< 0.01¹

< 0.01¹

CAIX

   Non elevated

11.6 (9.8-13.5)

0.06

21.3 (20.0-22.6)

< 0.01

   Elevated

8.1 (5.6-10.6)

15.9 (12.8-19.0)

CTC positive

CAIX

   Non elevated

11.0(8.7-13.1)

< 0.05

16.2 (14.0-18.4)

< 0.05

   Elevated

7.1(5.2-9.0)

11.8 (9.5-14.1)