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Figure 7 | Breast Cancer Research

Figure 7

From: Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Figure 7

Impact of 14-3-3ζ knockdown and FOXM1 expression on signature genes and proliferation of tamoxifen-resistant cells. (a) Expression of 14-3-3ζ, 14-3-3ζ signature genes, and FOXM1 in MCF-7 tamoxifen-resistant cells with siRNA knockdown of 14-3-3ζ and/or overexpression of FOXM1. (b) Cell viability monitored after 96 hours of vehicle or tamoxifen (Tam) treatment in tamoxifen-resistant cells with knockdown of 14-3-3ζ and/or overexpression of FOXM1. Control cells transfected with control siRNA were taken as 100%.

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Breast Cancer Research

ISSN: 1465-542X

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