Figure 2

Schematic representation of the different integrin heterodimers expressed in mammary epithelial cells. In the mammary ducts, most integrins are concentrated at sites of contact between the mammary basement membrane and myoepithelial cells. However, luminal epithelial cells also express the α2β1, α3β1, α6β1 and α6β4 heterodimers at cell-cell junctions.