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Table 1 Correlation of FOXP3 Treg with clinicopathological parameters and CXCL12 expression

From: Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers

  Treg < 15 Treg ≥15 P-value
Tumour size (mm)    
Median 21.2 23.8 0.571
Tumour grade    < 0.001
1 56 (22%) 25 (11%)  
2 123 (47%) 84 (38%)  
3 80 (31%) 115 (51%)  
Nodal status    0.062
Negative 154 (59%) 109 (51%)  
Positive 107 (41%) 107 (49%)  
ER    0.025
Negative 73 (28%) 81 (38%)  
Positive 189 (72%) 135 (62%)  
HER2    0.002
Negative 238 (97%) 186 (90%)  
Positive 7 (3%) 20 (10%)  
CXCL12    0.008
Negative 51 (41%) 27 (25%)  
Positive 74 (59%) 83 (75%)  
Endocrine Rx    0.255
Negative 99 (37%) 72 (32%)  
Positive 167 (63%) 151 (68%)  
Chemotherapy    0.148
Negative 168 (64%) 127 (57%)  
Positive 96 (35%) 95 (43%)  
  1. ER, estrogen receptor; Rx, therapy.
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Breast Cancer Research

ISSN: 1465-542X

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