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Figure 1 | Breast Cancer Research

Figure 1

From: miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention

Figure 1

Comparison of H2AFX status in MCF-7 vs. HeLa cells. (a) Real-time polymerase chain reaction analysis of gene copy number between the two cell lines using RNase P as an endogenous control. (b) Comparison of transcript expression using TaqMan assay for H2AX (Hs01573336_s1). (c) Confocal images of subcellular localization of H2AX and γ-H2AX before and after etoposide (10 μmol/l) treatment. (d) Fold difference in hsa-miR-24-2 expression using RNU 44 (Assay ID 001094; PN 4427975) for normalization. PI, propidium iodide.

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Breast Cancer Research

ISSN: 1465-542X

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