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Table 9 Relative risk of other second cancers* among patients given radiation therapy, by age-at- risk

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-risk RRaunadjusted for chemotherapy and hormonal therapy (95% CIb) RRaadjusted for chemotherapy and hormonal therapy (95% CIb) Cases/women with radiotherapy Cases/women with no radiotherapy
<50 2.12 (0.30, 15.07) 1.64 (0.22, 12.10) 3/569 (0.5%) 2/607 (0.3%)
50 to 64 1.67 (0.71, 3.91) 1.46 (0.62, 3.43) 11/926 (1.2%) 11/1,154 (1.0%)
65+ 2.07 (0.98, 4.35)** 2.04 (0.96, 4.35) 15/482 (3.1%) 16/1,022 (1.6%)
  1. * Other second cancers are all second cancers other than contralateral breast cancer and leukaemia.
  2. ** P = 0.055.
  3. a Relative risk is calculated based on a follow-up of five or more years.
  4. b Confidence interval.