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Table 4 Relative risk of all second cancers among patients given radiotherapy, by age-at-treatment

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment (years)

RRaunadjusted for chemotherapy and hormonal therapy (95% CIb)

RRaadjusted for chemotherapy and hormonal therapy (95% CIb)

Cases/women with radiotherapy

Cases/women with no radiotherapy

<50

0.96 (0.60, 1.56)

0.87 (0.54, 1.43)

32/584 (5.5%)

45/632 (7.1%)

50 to 64

1.43 (0.88, 2.31)

1.35 (0.83, 2.20)

35/549 (6.4%)

37/687 (5.4%)

65+

1.83 (0.65, 5.14)

1.69 (0.60, 4.76)

6/134 (4.5%)

12/494 (2.4%)

All

1.22 (0.88, 1.69)

1.14 (0.82, 1.58)

73/1,267 (5.8%)

94/1,813 (5.2%)

  1. a Relative risk is calculated based on a follow-up of five or more years.
  2. b Confidence interval.