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Table 4 Relative risk of all second cancers among patients given radiotherapy, by age-at-treatment

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment (years) RRaunadjusted for chemotherapy and hormonal therapy (95% CIb) RRaadjusted for chemotherapy and hormonal therapy (95% CIb) Cases/women with radiotherapy Cases/women with no radiotherapy
<50 0.96 (0.60, 1.56) 0.87 (0.54, 1.43) 32/584 (5.5%) 45/632 (7.1%)
50 to 64 1.43 (0.88, 2.31) 1.35 (0.83, 2.20) 35/549 (6.4%) 37/687 (5.4%)
65+ 1.83 (0.65, 5.14) 1.69 (0.60, 4.76) 6/134 (4.5%) 12/494 (2.4%)
All 1.22 (0.88, 1.69) 1.14 (0.82, 1.58) 73/1,267 (5.8%) 94/1,813 (5.2%)
  1. a Relative risk is calculated based on a follow-up of five or more years.
  2. b Confidence interval.