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Figure 4 | Breast Cancer Research

Figure 4

From: Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator

Figure 4

Effects of ERβ on ARNT binding with HIF-1α. HEK293 cells in 100 mm2 dish were cotransfected with GFP-HIF-1α (10 μg) and hERβ (10 or 20 μg) or ARNT plasmid (10 μg) as indicated. Cell lysates were immunoprecipitated with anti-HIF-1α antibody and precipitated proteins were analyzed by immunoblots with anti-HIF-1α (top) or anti-ARNT antibody (bottom). Shown are representative results from two to three separate experiments.

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Breast Cancer Research

ISSN: 1465-542X

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