Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

Table 3 Autoantibodies in cancer patient sera to MUC1 glycoforms correlate with age when sera were taken

		Sera from patients with benign breast disease used to define cut-off		Sera from age-matched healthy females used to define cut-off
		All positives¹	Strong positives²	All positives	Strong positives
		*P = 0.001*	*P = 0.001*	*P = 0.007*	*P = 0.003*
Age sera taken	N	n (%)	n (%)	n (%)	n (%)
<50	63³	7 (11)	3 (5)	14 (22)	5 (8)
50 to 59	132	33 (25)	27 (20)	31 (24)	21 (16)
60 to 69	136	57 (42)	46 (34)	51 (38)	39 (29)
70+	64	27 (42)	21 (33)	27 (42)	15 (23)

¹ Sera were defined as all positive if two standard deviations or higher than the mean fluorescence for at least one feature.
² Sera was defined as strong positive if four standard deviations or higher than the mean fluorescence for at least one feature.
³ Total number in age group

ISSN: 1465-542X