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Table 3 Autoantibodies in cancer patient sera to MUC1 glycoforms correlate with age when sera were taken

From: Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

   Sera from patients with benign breast disease used to define cut-off Sera from age-matched healthy females used to define cut-off
   All positives1 Strong positives2 All positives Strong positives
   P = 0.001 P = 0.001 P = 0.007 P = 0.003
Age sera taken N n (%) n (%) n (%) n (%)
<50 633 7 (11) 3 (5) 14 (22) 5 (8)
50 to 59 132 33 (25) 27 (20) 31 (24) 21 (16)
60 to 69 136 57 (42) 46 (34) 51 (38) 39 (29)
70+ 64 27 (42) 21 (33) 27 (42) 15 (23)
  1. 1 Sera were defined as all positive if two standard deviations or higher than the mean fluorescence for at least one feature.
  2. 2 Sera was defined as strong positive if four standard deviations or higher than the mean fluorescence for at least one feature.
  3. 3 Total number in age group