Table 2 Univariate and multivariate Cox regression analysis of factors associated with relapse-free survival in triple negative breast cancer

Age

   <35 years

1

-

   ≥35 years

0.77

0.33 to 1.76

0.529

Performance status

   ECOG0

1

-

   ECOG1

1.41

0.54 to 3.70

0.483

   ECOG2

4.29

0.83 to 22.17

0.082

Initial clinical stage

   IIA, IIB

1

1

   IIIA

9.75

1.30 to 73.30

0.027

7.51

0.98 to 57.83

0.053

   IIIB

9.59

1.18 to 77.94

0.034

7.72

0.92 to 64.93

0.060

   IIIC

18.59

2.37 to 146.04

0.005

14.75

1.74 to 125.11

0.014

Pathologic N stage

   pN0

1

1

   pN1

3.79

1.47 to 9.77

0.006

5.87

2.08 to 16.59

0.001

   pN2

4.14

1.33 to 12.88

0.014

4.95

1.45 to 16.91

0.011

   pN3

6.51

2.09 to 20.26

0.001

7.54

2.14 to 26.56

0.002

bcl-2

   Negative

1

-

   Positive

0.87

0.43 to 1.76

0.691

p53

   Negative

1

-

   Positive

1.05

0.52 to 2.16

0.885

Histologic grade

   II

1

1

   III

3.37

1.03 to 11.06

0.045

2.04

0.57 to 7.37

0.275

Ki-67

   Low Ki-67

1

1

   High Ki-67

4.64

1.41 to 15.22

0.011

7.82

2.18 to 28.13

0.002

   Continuous ^a

1.02

1.01 to 1.03

0.003

-