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Figure 2 | Breast Cancer Research

Figure 2

From: Quantification and clinical relevance of gene amplification at chromosome 17q12-q21 in human epidermal growth factor receptor 2-amplified breast cancers

Figure 2

Kaplan-Meier curves for relapse-free survival (RFS) and overall survival (OS). (a) Estrogen receptor/progesterone receptor (ER/PR) status. Blue line indicates ER- and PR-negative (ER-/PR-) status; black line indicates ER-, PR- or ER/PR-positive (ER-/PR+, ER+/PR- or ER+/PR+) status. (b) Topoisomerase IIα (TOP2A) amplification. Blue line indicates deleted or nonamplified (normal) TOP2A (TOP2A Del/N); black line indicates amplified TOP2A (TOP2A Amp). For RFS, P = 0.159; for OS, P = 0.132. (c) TOP2A and ER/PR status. Blue line indicates ER- and PR-negative (ER-/PR-) and deleted or nonamplified TOP2A (TOP2A Del/N); black line indicates ER-, PR-, or ER/PR-positive (ER-/PR+, ER+/PR- and ER+/PR+) status and amplified TOP2A (TOP2A Amp). For RFS, P = 0.001; for OS, P = 0.008.

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Breast Cancer Research

ISSN: 1465-542X

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