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Table 2 Distribution of patients and controls by age, race or ethnicity, and study centera

From: Rare, evolutionarily unlikely missense substitutions in CHEK2contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study

Distributions Patients, n(%) Controls, n(%)
Age range, yr   
   ≤30 106 (8.1%) 66 (6.0%)
   31-35 322 (24.7%) 171 (15.4%)
   36-40 434 (33.3%) 231 (20.8%)
   41-45 441 (33.8%) 199 (17.9%)
   46-50 0 (0.0%) 230 (20.7%)
   51-55 0 (0.0%) 212 (19.1%)
Total 1,303 (100.0%) 1,109 (100.0%)
Race or ethnicity   
   Caucasian 843 (64.7%) 956 (86.2%)
   East Asian 204 (15.7%) 70 (6.3%)
   Latina 158 (12.1%) 47 (4.2%)
   Recent African ancestry 98 (7.5%) 36 (3.2%)
Total 1,303 (100.0%) 1,109 (100.0%)
Study center   
   Breast CFR Australia 588 (45.1%) 513 (46.3%)
   Breast CFR Canada 302 (23.2%) 461 (41.6%)
   Breast CFR Northern California 413 (31.7%) 135 (12.2%)
Total 1,303 (100.0%) 1,109 (100.0%)
  1. a Patients and controls excluded because of poor mutation-screening performance are not included; percentage data are the percentages of the total number of patient or control DNA in the category indicated that met the mutation-screening quality control criterion; Breast CFR, Breast Cancer Family Registry.