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Figure 4 | Breast Cancer Research

Figure 4

From: Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer

Figure 4

Quantitative analysis of CST6 methylation by pyrosequencing. (A) Representative examples of pyrosequencing are shown in tumor and matched normal tissues. Percent indicates the quantity of methylation at each CpG locus across all 13 CpG dinucleotides. (B) The quantities of methylated CpGs in IBC show a significant association with the cystatin M loss (P = 0.008) and ER loss (P = 0.0002), but not with the PR (P = 0.64) or HER4 loss (P = 0.87). The negative and positive indicate the presence and absence of expression of each protein, respectively. Error bars indicate a standard deviation.

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Breast Cancer Research

ISSN: 1465-542X

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