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Table 3 Receptor conversion for ERα, PR (10% threshold) and HER2 in distant breast cancer metastases according to site

From: Receptor conversion in distant breast cancer metastases

   % conversion
   ERα PR HER2
  N N (%) N (%) N(%)
Brain 44 6 (13.7) 16 (36.3)* 1 (2.3)
Lung 43 4 (9.4) 8 (18.6) 2 (4.7)
Liver 63 8 (12.7) 26 (41.2)* 6 (9.5)
Skin 76 5 (6.6) 17 (22.3) 2 (2.6)
Gastro-intestinal 7 1 (14.3) 3 (42.9)* 1 (14.3)
  1. * statistically significantly more often than for lung and skin metastases (P = 0.04, chi-square test).
  2. ERα, estrogen receptor alpha; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.