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Figure 7 | Breast Cancer Research

Figure 7

From: Penta-O-galloyl-β-D-glucose induces G1arrest and DNA replicative S-phase arrest independently of P21 cyclin-dependent kinase inhibitor 1A, P27 cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple-negative xenograft growth

Figure 7

PGG intake by oral gavage inhibits MDA-MB231 tumor growth in female athymic nude mice. Starting 4 days after cell inoculation, PGG (20 mg/kg) was gavaged with 2% Tween-80 as vehicle to these animals once a day. (a) Body weight. (b) Tumor volume. Values are mean ± standard deviation (n = 10 mice per group). Statistical significance: analysis of variance PGG effect on tumor size, P < 0.0001. PGG, penta-O-galloyl-β-D-glucose.

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Breast Cancer Research

ISSN: 1465-542X

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