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Table 3 WST-1 proliferation assay for BT474 cells treated with trastuzumab and tamoxifen

From: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

  Fraction affected  
Dose Trastuzumab Tamoxifen Tzmab + Tam Combination index
0.2 0.27 ± 0.006 0.20 ± 0.028 0.39 ± 0.020 1.27 ± 0.212
0.4 0.49 ± 0.009 0.21 ± 0.022 0.60 ± 0.038 0.26 ± 0.072
0.6 0.58 ± 0.012 0.34 ± 0.040 0.69 ± 0.026 0.13 ± 0.027
1 0.64 ± 0.017 0.36 ± 0.021 0.75 ± 0.021 0.10 ± 0.017
5 0.66 ± 0.012 0.48 ± 0.015 0.82 ± 0.022 0.19 ± 0.047
10 0.68 ± 0.012 0.64 ± 0.012 0.90 ± 0.012 0.07 ± 0.016
  1. Doses of trastuzumab (Tzmab) and tamoxifen (Tam) in μg/ml and μM, respectively. Each value is the mean of three independent experiments (with eight replicate wells for each treatment) ± standard error.