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Table 2 WST-1 proliferation assay for BT474 cells treated with atRA and tamoxifen

From: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

  Fraction affected  
Dose atRA Tamoxifen atRA + Tam Combination index
0.2 0.21 ± 0.012 0.16 ± 0.059 0.33 ± 0.015 0.53 ± 0.099
0.4 0.26 ± 0.075 0.23 ± 0.049 0.46 ± 0.020 0.27 ± 0.066
0.6 0.37 ± 0.026 0.29 ± 0.075 0.51 ± 0.035 0.24 ± 0.062
1 0.47 ± 0.043 0.33 ± 0.032 0.60 ± 0.027 0.16 ± 0.048
5 0.51 ± 0.067 0.42 ± 0.029 0.62 ± 0.050 0.64 ± 0.072
10 0.53 ± 0.071 0.59 ± 0.045 0.69 ± 0.050 0.61 ± 0.106
  1. Doses of all-trans retinoic acid (atRA) and tamoxifen (Tam) in μM. Each value is the mean of three independent experiments (with eight replicate wells for each treatment) ± standard error.