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Figure 9 | Breast Cancer Research

Figure 9

From: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

Figure 9

Effect of treatment of BT474 cells on receptor signaling. Effect of all-trans retinoic acid (atRA), trastuzumab or the combination on HER2 expression level and activity, on AKT expression level and activity, on mitogen-activated protein kinase (MAPK) expression level and activity, and on expression levels of retinoic acid receptor (RAR)α, RARβ, retinoid X receptor (RXR)α and RXRβ in BT474 cells. Drugs used at indicated concentrations. pHER2, pMAPK and pAKT, phospho-HER2, phospho-MAPK and phospho-AKT, respectively.

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Breast Cancer Research

ISSN: 1465-542X

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