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Figure 1 | Breast Cancer Research

Figure 1

From: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

Figure 1

Cell cycle analysis. BT474 cells were either untreated or treated with vehicle (ethanol + PBS), 1 μM all-trans retinoic acid (atRA), 1 μg/ml trastuzumab, 1 μM tamoxifen, 1 μM atRA + 1 μg/ml trastuzumab (Tzmab), 1 μM atRA + 1 μM tamoxifen (Tam), 1 μg/ml trastuzumab (Tzmab) + 1 μM tamoxifen (Tam), or 1 μM atRA + 1 μg/ml trastuzumab (Tzmab) + 1 μM tamoxifen (Tam). On day 2 following treatment, both floating and adherent cells were collected and fixed. The percentages of cells in the G0/G1, S, and G2/M phases of the cell cycle were determined by flow cytometric analyses. Results are mean of three independent experiments ± standard error.

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Breast Cancer Research

ISSN: 1465-542X

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