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Table 5 Analysis of cell invasion following transient transfection with tenascin-C isoforms

From: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women

  

Cell line

Isoform

Time (hours)

MCF-7

T-47D

MDA-MB-231

GI-101

ZR-75-1

TNC-S

12

NS

NS

NS

NS

NS

 

24

NS

NS

NS

NS

NS

 

36

NS

NS

NS

NS

NS

 

48

NS

NS

NS

NS

NS

TNC-9/14/16

12

NS

NS

NS

NS

NS

 

24

NS

NS

NS

NS

NS

 

36

P <0.05 (NS)

NS (NS)

NS (NS)

P < 0.05 (<0.05)

NS (NS)

 

48

P < 0.001 (<0.05)

NS (NS)

NS (NS)

P < 0.001 (0.05)

NS (NS)

TNC-14/AD1/16

12

NS

NS

NS

NS

NS

 

24

P < 0.05 (NS)

P < 0.05 (NS)

P < 0.01 (NS)

NS (NS)

NS (NS)

 

36

P < 0.001 (<0.001)

P < 0.001 (<0.001)

P < 0.001 (<0.01)

NS (NS)

NS (NS)

 

48

P < 0.001 (<0.001)

P < 0.001 (<0.001)

P < 0.001 (<0.001)

P < 0.01 (NS)

NS (NS)

  1. Significance at 12-hour intervals relative to vector-only controls (relative to TNC-S). NS, not significant.