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Figure 7 | Breast Cancer Research

Figure 7

From: Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors

Figure 7

The role of the c(RGDfK) moiety in driving Bchl-D accumulation within tumors. CD-1 nude, female mice (n = 3) bearing an orthotopically grafted, large MDA-MB-231-RFP tumors were intravenously injected with 9 mg/kg STL-7012. Drug accumulation was monitored, by means of fluorescence imaging, for up to three days and a representative animal is shown. Upper panel - near infrared (NIR) fluorescence images indicate bacteriochlorophyll derivative (Bchl-D) distribution and lower panel - Red fluorescence images indicate tumor location.

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Breast Cancer Research

ISSN: 1465-542X

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