Table 1 Clinical characteristics of developmental stage-specific breast cancers
From: The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis
Stage | Increased risk (tumor subtype)* | Clinical characteristics |
|---|---|---|
Pregnancy | ER- | High stage diagnosis |
| Â | Â | High grade |
| Â | Â | Often metastatic |
Postmenopause | ER+ | Lower grade at diagnosis |
| Â | Â | Respond to anti-hormone therapies |
Postmenopause | ER- | High stage diagnosis |
with obesity | Â | Poor patient survival rate |