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Table 4 Predictive factors for relapse-free survival*

From: Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers

Variable

Pvalue

T stage

< 0.001

N stage

< 0.001

Histologic grade

0.033

ER

0.052

PR

0.076

HER2

0.016

Ki-67

0.015

PTEN

0.397

PI3K-p110α

0.058

p-Akt

0.681

p-p70S6K

0.342

p-S6

0.504

p-Raf

0.729

p-p44/42 MAPK

0.366

HSP90

0.039

  1. *Based on univariate analysis. Variables found to be significant (P < 0.05) are shown in bold.ER = estrogen receptor; HER2 = human epidermal growth factor receptor-2; HSP90 = heat-shock protein 90; MAPK = mitogen-activated protein kinase; PI3K = phosphatidylinositol-3-kinase; PR = progesterone receptor; PTEN = phosphatase and tensin homologue deleted on chromosome 10.
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Breast Cancer Research

ISSN: 1465-542X

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