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Table 4 Predictive factors for relapse-free survival*

From: Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers

Variable Pvalue
T stage < 0.001
N stage < 0.001
Histologic grade 0.033
ER 0.052
PR 0.076
HER2 0.016
Ki-67 0.015
PTEN 0.397
PI3K-p110α 0.058
p-Akt 0.681
p-p70S6K 0.342
p-S6 0.504
p-Raf 0.729
p-p44/42 MAPK 0.366
HSP90 0.039
  1. *Based on univariate analysis. Variables found to be significant (P < 0.05) are shown in bold.ER = estrogen receptor; HER2 = human epidermal growth factor receptor-2; HSP90 = heat-shock protein 90; MAPK = mitogen-activated protein kinase; PI3K = phosphatidylinositol-3-kinase; PR = progesterone receptor; PTEN = phosphatase and tensin homologue deleted on chromosome 10.