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Table 5 Univariate logistic regression analysis of factors affecting tumor response rate (ZIO 50%)

From: Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins

  

Odds ratio

(95% CI)

P

After EC + DOC

    
 

Age (years)

   
 

   <51

1.000

  
 

   51≤

0.800

(0.192-3.333)

0.7592

 

Cancer stage

   
 

   II

1.000

  
 

   III, IV

5.750

(1.028-32.174)

0.0465

 

Tumor stage

   
 

   T2

1.000

  
 

   T3

7.833

(1.279-47.964)

0.0260

 

Nodal status

   
 

   N-

1.000

  
 

   N+

6.286

(0.730-54.110)

0.0942

 

Subtype

   
 

   Luminal A, B

1.000

  
 

   HER2, Basal-like

3.958

(0.913-17.154)

0.0659

 

DDR score

   
 

   0, 1, 2

1.000

  
 

   3, 4

9.423

(1.729-51.359)

0.0095

  1. CI, confidence interval; DDR, DNA Damage Response; DOC, docetaxel; EC, epirubicin plus cyclophosphamide; HER, human epidermal growth factor receptor.
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Breast Cancer Research

ISSN: 1465-542X

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