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Table 3 Correlation between DDR score and tumor response rate (ZIO 50%)

From: Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins

  DDR score
  0 1 2 3 4 Total
After EC       
   CR 1 0 1 0 0 2
   PR 1 12 14 9 2 38
   SD 0 3 8 3 4 18
   Total 2 15 23 12 6 58
       P = 0.0639
After EC + DOC       
   CR 1 1 3 1 0 6
   PR 1 13 19 9 2 44
   SD 0 0 1 2 4 7
   Total 2 14 23 12 6 57
       P = 0.0031
  1. P values are from the Spearman's rank correlation test. CR, complete response; DDR, DNA damage response; EC, epirubicin plus cyclophosphamide; PR, partial response; SD, stable disease.