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Table 3 Correlation between DDR score and tumor response rate (ZIO 50%)

From: Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins

 

DDR score

 

0

1

2

3

4

Total

After EC

      

   CR

1

0

1

0

0

2

   PR

1

12

14

9

2

38

   SD

0

3

8

3

4

18

   Total

2

15

23

12

6

58

      

P = 0.0639

After EC + DOC

      

   CR

1

1

3

1

0

6

   PR

1

13

19

9

2

44

   SD

0

0

1

2

4

7

   Total

2

14

23

12

6

57

      

P = 0.0031

  1. P values are from the Spearman's rank correlation test. CR, complete response; DDR, DNA damage response; EC, epirubicin plus cyclophosphamide; PR, partial response; SD, stable disease.