Skip to main content

Table 1 Correlation of expression of PIPKIγ protein with different biomarkers

From: Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer

Biomarker PIPKIγ negative and weak vs. strong staining
  Spearman's correlation coefficient Pvalue Number of cases
E-cadherin negative vs. weak and strong staining 0.106 0.046 351
ER at 1% cut-off point -0.256 0.000003 327
PR at 1% cut-off point -0.298 0.000001 256
EGFR (HER1) negative vs. weak and strong staining 0.262 0.000003 306
HER2/neu 0.171 0.003 309
Nottingham Grade 0.185 0.001 346
Tumour size 0.025 0.648 349
Nodal status 0.012 0.828 314
  1. EGFR = epidermal growth factor receptor; ER = estrogen receptor; HER2 = human epidermal growth factor receptor 2; PIPKIγ = type I gamma phosphatidylinositol phosphate kinase; PR = progesterone receptor.