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Table 4 Age-adjusted incidence rate (AAIR) of invasive and in situ breast cancer according to hormone therapy (HT) use at follow-up in 2000-2001 among menopausal women in the California Teachers Study

From: Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort

Period

Never HT

Past HT

Current E

Current EP

 

AAIR (95% CI)

AAIR (95% CI)

AAIR (95% CI)

AAIR (95% CI)

 

Invasive breast cancer

 

2001-02

369.3 (285.6-452.9)

561.1 (432.4-689.8)

534.9 (424.7-645.1)

665.8 (565.9-765.7)

2003-05

343.7 (272.8-414.5)

340.0 (265.6-414.4)

406.4 (324.7-488.0)

461.9 (392.5-531.4)

% change

-6.9% P = 0.33

-39.4% P = 0.003

-24.0% P = 0.030

-30.6% P = 0.001

 

In Situ breast cancer

 

2001-02

86.6 (44.0-129.1)

100.5 (32.4-168.6)

137.7 (83.2-192.3)

135.0 (95.2-174.9)

2003-05

107.2 (63.1-151.3)

99.5 (60.3-138.8)

123.6 (67.3-179.9)

115.5 (78.1-152.8)

% change

23.8% P = 0.26

-1.0% P = 0.49

-10.2% P = 0.35

-14.4% P = 0.22

  1. CI = confidence interval; E = estrogen only; EP = estrogen and progestin combined therapy.