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Figure 2 | Breast Cancer Research

Figure 2

From: PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

Figure 2

Differentially expressed genes between sensitive and resistant cell lines. Results of analysis of variance (ANOVA) identifying 450 differentially expressed genes between sensitive cell lines (IC50 < 150 nM) and resistant cell lines (IC50 > 1,000 nM). Retinoblastoma and cyclin D1 expression were higher in, and CDKN2A (p16) was lower in, sensitive cell lines. Full results of the ANOVA are available in the Additional data files.

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