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Table 2 Multivariate analysis (logistic regression and Cox regression analysis)

From: Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapy

 

correlation with pCR

correlation with survival

 

OR

95% CI

p

hazard ratio

95% CI

p

biology-based tumor type

  

0.258a

  

< 0.0001a

   HR+/HER2-

1.00

  

1.00

  

   HR+/HER2+

14.28

1.05-194.31

0.046

1.88

0.39-9.04

0.432

   HR-/HER2+

5.35

0.25-116.83

0.287

16.78

5.75-48.97

< 0.0001

   HR-/HER2-

6.01

0.53-67.84

0.147

4.24

1.62-11.12

0.003

Ki67

      

   <= 20%

1.00

     

   > 20%

10.37

1.29-83.28

0.028

-

-

-

CK5/6

      

   negative

1.00

     

   positive

0.51

0.04-7.57

0.627

-

-

-

therapy arm

      

   ADoc

1.00

     

   ACDoc

11.97

1.17-122.16

0.036

-

-

-

grade

      

   G1-2

1.00

     

   G3

5.59

0.93-33.70

0.061

-

-

-

ypN

      

   cN0

   

1.00

  

   cN1-2

-

-

-

2.77

1.24-6.18

0.013

pCR

      

   no pCR

   

1.00

  

   pCR

-

-

-

0.18

0.02-1.43

0.104

  1. OR: odds ratio; CI: confidence interval; a: overall significance.
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Breast Cancer Research

ISSN: 1465-542X

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