Figure 4

The relative sensitivity of six cell lines to three proteasome inhibitors is the same as that to Z-LLNle-CHO. Cells were treated with MG132, bortezomib, or lactacystin at indicated concentrations for 72 hours before cell viability was measured by MTS assay. Results represent the mean ± standard deviation of three independent experiments. Please note the relative cellular sensitivity of the same six breast cancer cell lines to three structurally unrelated proteasome inhibitors was the same as that to Z-LLNle-CHO in Figure 1.