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Table 1 Patient characteristics

From: Tumor aromatase expression as a prognostic factor for local control in young breast cancer patients after breast-conserving treatment

  RT-PCR series Whole series  
Total n % n % P
Family history of breast cancer (MD = 0 and 1)a 0.77
   Without 42 79 198 77  
   With 11 21 58 23  
Age (MD = 0 and 0)a  
   Median (min-max) in years 37 (23–40)   37 (23–40)   0.71
   ≤ 35 years old 37 70 176 68 0.85
   > 35 years old 16 30 81 32  
Clinical T stage (MD = 0 and 0)a 0.0496
   cT0–1 31 58 186 72  
   cT2 22 42 71 28  
Clinical N stage (MD = 0 and 0)a 0.70
   N0 52 98 246 96  
   N1 1 2 11 4  
Type of invasive carcinoma (MD = 0 and 0)a 0.18b
   Ductal 46 87 223 87  
   Lobular 6 11 16 6  
   Other 1 2 18 7  
Histologic grade (MD = 0 and 1)a 0.03b
   1–2 14 26 110 43  
   3 36 68 120 47  
   Unclassifiable 3 6 26 10  
Estrogen receptor (ER) (MD = 6 and 37)a 0.59
   ER- 10 21 55 25  
   ER+ 37 79 165 75  
Progesterone receptor (PR) (MD = 6 and 39)a 0.84
   PR- 9 19 39 18  
   PR+ 38 81 179 82  
Hormone receptors (HRs) (MD = 6 and 37)a 0.87
   HR- 7 15 35 16  
   HR+ 40 85 185 84  
Lymphovascular involvement (MD = 3 and 43)a 0.0004
   Absent 33 66 188 88  
   Present 17 34 26 12  
Histologic T stage (MD = 5 and 12)a 0.89
   pT1 34 71 176 72  
   pT2 14 29 69 28  
Histologic N stage (MD = 0 and 34)a 0.06
   pN0 31 58 182 73  
   pN1–3 22 42 41 27  
Surgical margins (MD = 4 and 10)a 0.10
   Satisfactory (≥ 3 mm) 32 65 129 52  
   Unsatisfactory 17 35 118 48  
Systemic therapy (MD = 0 and 0)a 0.0001
   None 16 30 151 59  
   Hormone therapy (HT) only 0 0 101 39  
   Chemotherapy ± HT 37 70 5 2  
Total RT dose (MD = 0)a  
   Median (min-max) in Gy 66 (50–75)   64 (0–80)   0.14
   < 60 Gy 13 25 101 39 0.043
   ≥ 60 Gy 40 75 156 61  
  1. Characteristics of the rt-PCR series (53 patients) in comparison to the whole population of consecutive patients with the same selection criteria treated over the same period (1988–1999) at the Institut Curie (257 patients). MD = missing data (both in the rt-PCR and in the whole series); total RT dose = total radiotherapy dose to the tumor bed (whole-breast radiotherapy dose + boost dose). a0.37 when the comparison excluded histologic types other than ductal or lobular. b0.05 when the comparison included all histologic grades.