Breast Cancer Research

Table 3 Allele frequencies of SWAN Genetics Study participants by race/ethnicity

From: Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women

		Estimated frequencies
Locus	Allele	All	African	White	Chinese	Japanese
17β-HSD
rs615942	G	0.52	0.64	0.47	0.55	0.56
	T	0.48	0.36	0.53	0.45	0.44
rs592389	A	0.50	0.41	0.475	0.56	0.56
	C	0.50	0.59	0.53	0.44	0.44
rs2830	A	0.50	0.59	0.53	0.44	0.44
	G	0.50	0.41	0.47	0.56	0.56
ESR1
rs9340799	A	0.72	0.73	0.65	0.77	0.82
	G	0.28	0.27	0.35	0.23	0.18
rs2234693	C	0.46	0.46	0.46	0.41	0.48
	T	0.54	0.54	0.54	0.59	0.52
rs728524	A	0.89	0.76	0.98	0.81	0.81
	G	0.11	0.24	0.02	0.19	0.188
rs3798577	C	0.46	0.41	0.48	0.45	0.45
	T	0.54	0.59	0.52	0.55	0.55
ESR2
rs1256030	C	0.61	0.75	0.57	0.70	0.58
	T	0.39	0.25	0.43	0.30	0.42
rs1255998	C	0.68	0.50	0.89	0.37	0.54
	G	0.32	0.50	0.11	0.63	0.46
rs1256049	A	0.18	0.11	0.02	0.45	0.30
	G	0.82	0.89	0.98	0.55	0.70
CYP1A1
rs2606345	A	0.37	0.18	0.66	0.06	0.05
	C	0.63	0.82	0.34	0.94	0.95
rs4646903	A	0.75	0.71	0.89	0.54	0.61
	G	0.25	0.29	0.11	0.46	0.39
rs1531163	A	0.88	0.66	0.95	0.84	0.80
	G	0.12	0.34	0.05	0.16	0.20
rs1048943	A	0.88	0.98	0.96	0.75	0.76
	G	0.12	0.02	0.04	0.25	0.24
CYP1B1
rs1800440	A	0.89	0.90	0.80	1.00	1.00
	G	0.11	0.10	0.20	0.004	0.006
rs162555	C	0.12	0.16	0.19	0.04	0.01
	T	0.88	0.84	0.81	0.96	0.99
rs1056836	C	0.69	0.33	0.59	0.88	0.86
	G	0.31	0.67	0.41	0.12	0.14
CYP19
rs700519	A	0.12	0.13	0.04	0.14	0.29
	G	0.88	0.88	0.96	0.86	0.71
rs2414096	A	0.43	0.25	0.50	0.46	0.32
	G	0.57	0.75	0.50	0.54	0.68
4947^a	A	0.52	0.71	0.55	0.39	0.49
	G	0.48	0.29	0.45	0.61	0.51
rs1008805	C	0.36	0.16	0.42	0.28	0.37
	T	0.64	0.84	0.58	0.72	0.63
rs2446405	A	0.32	0.52	0.18	0.47	0.45
	T	0.68	0.48	0.82	0.53	0.55
rs936306	C	0.73	0.40	0.85	0.70	0.60
	T	0.27	0.60	0.15	0.30	0.40
rs2445759	G	0.96	0.92	0.93	1.00	1.00
	T	0.04	0.08	0.07	0.004	0.003
rs749292	A	0.44	0.51	0.44	0.50	0.36
	G	0.56	0.49	0.56	0.50	0.64

^aNo corresponding dbsnp rs number; commonly referred to as CYP194947.

Back to article page

ISSN: 1465-542X

Contact us

Submission enquiries: journalsubmissions@springernature.com